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TSHA Institutional Ownership

Top institutional (13F) holders of TSHA and 5%+ (13D/G) positions, sourced from SEC EDGAR.

Institutional owners
39
Institutional value
$900.28M
Top holder
GOLDMAN SACHS GROUP INC

Top holders

HolderStakeFiledValue
GOLDMAN SACHS GROUP INCinvestment advisor7.0%Aug 14, 2026$154.68M
BlackRock, Inc.holding company6.4%Aug 7, 2026$140.91M
MORGAN STANLEYholding company5.1%Aug 13, 2026$112.28M
FMR LLCinvestment advisor4.1%Aug 13, 2026$90.82M
Vanguard Capital Managementinvestment advisor3.8%Aug 13, 2026$84.98M
STATE STREET CORPORATIONholding company3.5%Sep 22, 2026$77.78M
GEODE CAPITAL MANAGEMENT, LLCinvestment advisor2.1%Nov 6, 2026$33.91M
D. E. Shaw & Co., Inc.investment advisor1.3%Aug 14, 2026$29.95M
WELLINGTON MANAGEMENT GROUP LLPinvestment advisor1.2%Aug 14, 2026$27.07M
Vanguard Portfolio Managementinvestment advisor1.0%Aug 13, 2026$21.38M
Norges Bankother0.7%Aug 12, 2026$15.21M
NORTHERN TRUST CORPinvestment advisor0.7%Aug 13, 2026$15.16M
CHARLES SCHWAB INVESTMENT MANAGEMENT INCinvestment advisor0.7%Aug 14, 2026$14.99M
MILLENNIUM MANAGEMENT LLCinvestment advisor0.7%Aug 14, 2026$14.48M
CITADEL ADVISORS LLCinvestment advisor0.5%Sep 1, 2026$11.67M
BANK OF AMERICA CORP /DE/holding company0.4%Aug 14, 2026$9.35M
JPMORGAN CHASE & COholding company0.2%Aug 12, 2026$5.16M
SUSQUEHANNA INTERNATIONAL GROUP, LLPinvestment advisor0.2%Aug 14, 2026$4.65M
UBS Group AGbank0.2%Aug 13, 2026$4.01M
Bank of New York Mellon Corpholding company0.2%Nov 5, 2026$3.6M
POLEN CAPITAL MANAGEMENT LLCinvestment advisor0.2%Aug 4, 2026$3.33M
Dimensional Fund Advisors LPinvestment advisor0.2%Nov 4, 2026$3.3M
Swiss National Bankinvestment advisor0.1%Aug 11, 2026$2.51M
WELLS FARGO & COMPANY/MNinvestment advisor0.1%Aug 14, 2026$2.27M
Point72 Asset Management, L.P.investment advisor0.1%May 15, 2026$2.06M

5%+ holders

Current stakes of 5% or more from Schedule 13D and 13G filings. A joint filing shows once, under its lead filer.

HolderFormStakeFiled
Peter Kolchinskyholding companywith RA Capital Healthcare Fund, L.P. and 2 othersSC 13G/A9.9%Aug 14, 2026
Roderick Wongholding companywith RTW Investments, LPSC 13G/A7.0%May 15, 2026
Roderick Wong, M.D.individualwith RTW Investments, LPSC 13G/A10.0%May 15, 2025
Ryan Wilderholding companywith Vestal Point Capital, LPSC 13G/A6.3%May 15, 2026
BlackRock, Inc.holding companySC 13G/A6.5%Jan 21, 2026
MORGAN STANLEYholding companywith Morgan Stanley Capital Services LLCSC 13G/A5.1%Aug 13, 2026
The Paul B. Manning Revocable Trust dated May 10, 2000otherwith BKB G2 Investments, LLC and 4 othersSC 13D/A5.6%Jun 4, 2025
GOLDMAN SACHS & CO. LLCbroker dealerwith THE GOLDMAN SACHS GROUP, INC.SC 13G5.1%Jul 3, 2025

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Source: SEC EDGAR Schedule 13D / 13G and 13F filings.